尼氏體(Nissl body)或稱尼氏小體是分布于神經細胞胞質內的三角形或橢圓形小塊狀物質，能被堿性染料如硫堇、亞甲藍、甲苯胺藍和焦油紫等染料染成紅紫色到紫藍色。
尼氏染色液(硫堇法)主要優點是操作簡便、染色穩定、適用范圍廣，可以用于石蠟組織切片的尼氏物質、神經元等的染色，尼氏體的存在和消失是神經細胞是否受損的重要指標，當發生腦炎、腦缺血、軸突反應等情況時，尼氏體會發生溶解甚至消失。    

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標題:Insulin alleviates lipopolysaccharide-induced cognitive impairment via inhibiting neuroinflammation and ferroptosis

成員:Miao Sun, Yang Li, Min Liu, Qingxiao Li, Likai Shi, Xianghan Ruan, Yuting Huo, Zhikang Zhou, Xiaoying Zhang, Yulong Ma, Weidong Mi

論文因子:5 發表期刊:EUROPEAN JOURNAL OF PHARMACOLOGY pmid:37479016

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標題:SM22α Deletion Contributes to Neurocognitive Impairment in Mice through Modulating Vascular Smooth Muscle Cell Phenotypes

成員:Xin Xu, Xiao-Qin Liu, Xin-Long Liu, Xu Wang, Wen-Di Zhang, Xiao-Fu Huang, Fang-Yue Jia, Peng Kong, Mei Han

論文因子:6.208 發表期刊:INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES pmid:37108281

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標題:Berberine modulates gut microbiota to attenuate cerebral ferroptosis induced by ischemia-reperfusion in mice

成員:Xinyu Wang, Jiamin Zhang, Sisi Wang, Zhengyang Song, Hongxia Sun, Fangquan Wu, Xiaohui Lin, Keke Jin, Xiaofeng Jin, Wantie Wang, Qiongqiong Lin, Fangyan Wang

論文因子:5.195 發表期刊:EUROPEAN JOURNAL OF PHARMACOLOGY pmid:37245860

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標題:Icariin reduces cognitive dysfunction induced by surgical trauma in aged rats by inhibiting hippocampal neuroinflammation

成員:Wang Lifeng, Peng Guanfa, Chen Li, Guo Mingling, Wang Bingyu, Zhang Yunmeng, Zhou Jianshun, Zhong Maolin, Ye Junming

論文因子:3 發表期刊:Frontiers in Behavioral Neuroscience pmid:37351155

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標題:Ozone rectal insufflation mitigates chronic rapid eye movement sleep deprivation-induced cognitive impairment through inflammation alleviation and gut microbiota regulation in mice

成員:Cheng Jie, Williams John P., Zhou Li, Wang Peng-Cheng, Sun Li-Na, Li Rui-Hua, An Jian-Xiong

論文因子:2.9 發表期刊:Medical Gas Research

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尼氏染色液(硫堇法)

尼氏染色液(硫堇法)